Sunday, May 2, 2010

How can diabetes "run" to the feet

A woman with diabetes, aged 75, more than 20 years history of diabetes, long-term use of various antidiabetic glibenclamide and traditional Chinese medicine, the last 3 years have been fasting plasma glucose of 12 to 15 mmol / L (220 to 270 mg / dl). Then right foot toe nail due to shear, resulting in long-term unhealed after local ulceration, necrosis of the great toe black color, so come to our hospital.

The initial diagnosis of patients admitted to hospital as a "type 2 diabetes and arteriosclerosis obliterans of lower limbs, diabetic foot five." In the treatment process, so that it bothers her a question: "how my diabetes 'run' to the feet go?" This sounds ridiculous, but it largely reflects the number of diabetes patients ignorance.

As people's living standards improve, the incidence of diabetes at an alarming pace, a variety of chronic complications of diabetes also increased, to become invisible killer threatening diabetes. Obliterans is involved diabetic complications surrounding a large blood vessels, as mentioned in the article at the beginning of the patients as arteriosclerosis obliterans developed to a certain extent, can lead to acral necrosis, severe cases leading to amputation, become disabled patients died an important reason.

Obliterans is a disease involving atherosclerosis and lead to chronic peripheral arterial occlusive disease. As the atherosclerotic plaque and its internal bleeding or plaque rupture, leading to the formation of blood clots and has the effect of secondary vascular stenosis or occlusion, leading to clinical manifestations such as limb ischemia. Disease is more common in the elderly, age 50 to more than 70 years, 20% of patients had diabetes. Patients with diabetes than those without the disease 11 times higher in patients with diabetes, and age of onset earlier, easier and far less impact on adjacent parts of the caliber arteries. Therefore, the diabetes "running" to the feet go, is not surprising.

Arteriosclerosis by symptoms can be divided into four phases:

Phase 1 patients may be in the lower limbs, feet numbness, coldness, leg soreness, especially in the lower leg significantly.

The first two pairs of lower limb blood flow reserve shortage, intense activity can not maintain an adequate blood flow, patients can be manifested as intermittent claudication, such as walking a short distance but was forced to stop because of pain, rest pain relief.

3, the further development of ischemia, residual blood flow below the resting metabolism of the needs of the time, showing resting pain, particularly at night obviously.

4 can not provide the necessary organizational survival of blood flow, peripheral and contact with skin lesions began to appear dystrophy, clinical manifestations of necrosis or acral gangrene.

If color Doppler ultrasound examination of both lower extremities results divided, the disease can be divided into four degrees:

Early lesions of vascular stenosis were 25% lower than the normal blood flow is less than 35% of normal;

Slightly lower than that of lesion stenosis of 25 to 50% less than the normal blood flow of 35 to 50%;

Normal coronary arteries with moderate stenosis of 50 to 75% of people, blood flow less than the normal 50 to 70%;

Severe stenosis of coronary arteries more than 75% lower than the normal person, normal blood flow is less than 70%.

Obliterans is the most serious damage caused acral necrosis, gangrene, especially in diabetic arteriosclerosis obliterans, diabetic foot disease is the most fundamental reason.

In case of diabetic foot patients, treatment up very difficult, so many patients are forced to amputation, to the inconvenience of life. Therefore, to remind the general diabetic patients must be early detection and treatment of arteriosclerosis obliterans, Once the symptoms mentioned above, should consult a doctor.

Now, with the continuous improvement of diagnosis, the disease has greatly increased the detection rate. Early by noninvasive - Color Doppler ultrasound can check arteries, vein diameter and flow rate, the quantitative orientation analysis, so that the disease is greatly improved diagnostic accuracy.

Once diagnosed with arteriosclerosis obliterans, patients should stop smoking (smoking can cause vascular spasm), treatment of lipid abnormalities, diabetes, limb skin to keep clean, dry and soft, to prevent the cold and injuries. Such as a local infection or trauma, should be dealt with expeditiously. In addition, a large number of current clinical application of vasodilator agents and anti-suppository, the more significant effect of early lesions. Also carried out in recent years, surgical treatment and interventional therapy with good results.

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